Pharmacokinetic Study of Epinephrine Hydrofluoroalkane (Primatene MIST) Metered-Dose Inhaler
نویسندگان
چکیده
منابع مشابه
Fluticasone propionate via the Diskhaler or hydrofluoroalkane-134a metered-dose inhaler on methacholine-induced airway hyperresponsiveness.
STUDY OBJECTIVE s: To compare the effect of 4 weeks of treatment with fluticasone propionate (FP), 100 micro g bid, delivered either via the Diskhaler (GlaxoSmithKline; Middlesex, UK) or a hydrofluoroalkane (HFA)-134a pressurized metered-dose inhaler (pMDI) on airway responsiveness. DESIGN A single-center, randomized, double-blind, double-dummy, placebo-controlled crossover study. SETTING O...
متن کاملSalmeterol administration by metered-dose inhaler alone vs metered-dose inhaler plus valved holding chamber.
STUDY OBJECTIVE To determine whether a spacer device designed as a valved holding chamber with a flow signal increases the efficacy of the long-acting beta(2)-agonist, salmeterol, in patients who use incorrect technique with metered-dose inhaler (MDI) alone. DESIGN Double-blind, randomized, placebo-controlled study. SETTING University hospital outpatient rooms. PATIENTS Twenty adult outpa...
متن کاملSalbutamol delivery from a hydrofluoroalkane pressurized metered-dose inhaler in pediatric ventilator circuits: an in vitro study.
STUDY OBJECTIVES The aim of our study was to determine the in vitro delivery of salbutamol from a pressurized metered-dose inhaler (pMDI) containing hydrofluoroalkane (HFA) propellant through various delivery devices to four models of a pediatric lung. DESIGN To determine the effect of electrostatic charge, delivery of salbutamol was initially assessed with a multistage liquid impinger (MSLI)...
متن کاملPrinciples of metered-dose inhaler design.
The pressurized metered-dose inhaler (pMDI) was introduced to deliver asthma medications in a convenient and reliable multi-dose presentation. The key components of the pMDI device (propellants, formulation, metering valve, and actuator) all play roles in the formation of the spray, and in determining drug delivery to the lungs. Hence the opportunity exists to design a pMDI product by adjusting...
متن کاملSalmeterol + Fluticasone propionate Seretide Metered Dose Inhaler
PRODUCT DESCRIPTION Salmeterol + Fluticasone propionate (Seretide) 25/50mcg Metered Dose Inhaler: Each single actuation provides salmeterol xinafoate equivalent to 25mcg of salmeterol and 50mcg of fluticasone propionate. Salmeterol + Fluticasone propionate (Seretide) 25/125mcg Metered Dose Inhaler: Each single actuation provides salmeterol xinafoate equivalent to 25mcg of salmeterol and 125mcg ...
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ژورنال
عنوان ژورنال: Journal of Aerosol Medicine and Pulmonary Drug Delivery
سال: 2020
ISSN: 1941-2711,1941-2703
DOI: 10.1089/jamp.2019.1577